Sequential Organ Failure Assessment: SOFA Score

Input

Important notes on point assignment are found below
PaO2
FIO2
Ventilatory Support
Platelets
Bilirubin
Blood Pressure
Glasgow Coma Score
Creatinine
24-Hour Urine Output

 

Results

Important: Inputs must be complete to perform calculation.
PaO2/FIO2
SOFA Score

Data action

     
 
Include literature references: Yes   No

Notes

  • Vasoactive drug dose criteria based on administration for at least one hour.
  • The SOFA score helps predict morbidity rather than mortality, though individuals with a score of 15 or more had a mortality rate of 90%1.

Equations used


PaO2/FIO2 = 100 * PaO2 / FIO2
 

SOFAScore = PaO2/FIO2Factor + PlateletsFactor + BilirubinFactor + BloodPressure + GlasgowComaScoreFactor + RenalFactor
 

Calculation details and variables

  • Equation parameters such as Ventilatory Support, have two or more discrete values that may be used in the calculation. The numbers in the parentheses, e.g. (0), represent the values that will be used.
  • PlateletsFactor is assigned values by this ordered logic:
    • If Platelets <20 x10(3)/mcL, PlateletsFactor = 4
    • Else if Platelets <50 x10(3)/mcL, PlateletsFactor = 3
    • Else if Platelets <100 x10(3)/mcL, PlateletsFactor = 2
    • Else if Platelets <150 x10(3)/mcL, PlateletsFactor = 1
    • Else PlateletsFactor = 0.
  • BilirubinFactor is assigned values by this ordered logic:
    • If Bilirubin <1.2 mg/dL, BilirubinFactor = 0
    • Else if Bilirubin <2 mg/dL, BilirubinFactor = 1
    • Else if Bilirubin <6 mg/dL, BilirubinFactor = 2
    • Else if Bilirubin <12 mg/dL, BilirubinFactor = 3
    • Else BilirubinFactor = 4.
  • GlasgowComaScoreFactor is assigned values by this ordered logic:
    • If Glasgow Coma Score >14 points, GlasgowComaScoreFactor = 0
    • Else if Glasgow Coma Score >12 points, GlasgowComaScoreFactor = 1
    • Else if Glasgow Coma Score >9 points, GlasgowComaScoreFactor = 2
    • Else if Glasgow Coma Score >5 points, GlasgowComaScoreFactor = 3
    • Else GlasgowComaScoreFactor = 4.
  • pafiFactor is assigned values by this ordered logic:
    • If PaO2/FIO2 ≤100 with Ventilatory Support pafiFactor = 4
    • Else if PaO2/FIO2 ≤200 with Ventilatory Support pafiFactor = 3
    • Else if PaO2/FIO2 ≤300 pafiFactor = 2
    • Else if PaO2/FIO2 ≤400 pafiFactor = 1
    • Else pafiFactor = 0
  • RenalFactor is assigned values by this ordered logic:
    • If Creatinine <1.2 mg/dL RenalFactor = 0
    • Else if Creatinine <2 mg/dL RenalFactor = 1
    • Else if Creatinine <3.5 mg/dL RenalFactor = 2
    • Else if Creatinine <5 mg/dL RenalFactor = 3
    • Else RenalFactor = 4
  • RenalFactor may also be set based on urine output:
    • If Urine Output <500 mL/day RenalFactor = 3
    • Else if Urine Output <200 mL/day RenalFactor = 4

References

  1. Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016 Feb 23;315(8):801-10. PubMed ID: 26903338 PubMedLink
  2. Vincent JL, de Mendonca A, Cantraine F, et al. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine. Crit Care Med. 1998 Nov;26(11):1793-800. PubMed ID: 9824069 PubMedLink

Associated Logical Observation Identifiers Names and Codes [LOINC]

Parameter LOINC's and Suggested Units
PaO2 11556-8 : mmHg      2703-7 : mmHg      19254-2 : mmHg      
FIO2 3150-0 : %      19993-5 : %      19992-7 : %      19994-3 : %      19996-8 : %      19995-0 : %      
Platelets 777-3 : x10^9/L      26515-7 : x10(3)/mcL      
Bilirubin 1975-2 : mg/dL      32303-0 : mmol/L      59828-4 : mg/dL      54363-7 : mcmol/L      58941-6 : mg/dL      
Glasgow Coma Score 9269-2 : score      35088-4 : score      
Creatinine 2160-0 : mg/dL      38483-4 : mg/dL      14682-9 : mcmol/L      22726-4 : mcmol/L      59826-8 : mcmol/L      
Urine Output 3167-4 : mL/day      9192-6 : mL/day      
SOFA Score 96790-1 : score      

 
This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.

Associated HCC ICD10-CM codes

Associated ICD9-CM codes

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