EBMcalc Medical Calculator

ROX Index (Respiratory rate--oxygenation)

Input

O₂Sat

FIO₂

Respiratory Rate

Result

Important: Inputs must be complete to perform calculation.

ROX Index

Decimal Precision

ROX Index Interpretation

>=4.88:

Reduced risk of intubation

>=3.85 and <4.88:

Indeterminant risk

<3.85:

Increased risk of intubation

Data action

Include literature references: Yes No

Equations used

ROXIndex = O₂Sat / (FIO₂ / 100) / RespiratoryRate

References

Roca O, Messika J, Caralt B, et al. Predicting success of high-flow nasal cannula in pneumonia patients with hypoxemic respiratory failure: The utility of the ROX index. J Crit Care. 2016 Oct;35:200-5. PubMed ID: 27481760
Gianstefani A, Farina G, Salvatore V, et al. Role of ROX index in the first assessment of COVID-19 patients in the emergency department. Intern Emerg Med. 2021 Mar 1:1–7. PubMed ID: 33646507
Roca O, Caralt B, Messika J, Samper M, et al. An Index Combining Respiratory Rate and Oxygenation to Predict Outcome of Nasal High-Flow Therapy. Am J Respir Crit Care Med. 2019 Jun 1;199(11):1368-1376. PubMed ID: 30576221

Associated Logical Observation Identifiers Names and Codes [LOINC]

Parameter	LOINC's and Suggested Units
O2Sat	2708-6 : % 2713-6 : % 51733-4 : % 59408-5 : %
FIO2	3150-0 : % 19993-5 : % 19992-7 : % 19994-3 : % 19996-8 : % 19995-0 : %
Respiratory Rate	9303-9 : breaths/min 9279-1 : breaths/min 76170-0 : breaths/min 19840-8 : breaths/min

This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.

Associated HCC ICD10-CM codes

J95.821

Acute postprocedural respiratory failure

J96.00

Acute respiratory failure unspecified

J96.01

Acute respiratory failure w/ hypoxia

J96.02

Acute respiratory failure w/ hypercapnia

I150.31

Acute diastolic (congestive) heart failure

I150.23

Acute on chronic systolic (congestive) heart failure

I150.30

Unspecified diastolic (congestive) heart failure

I150.33

Acute on chronic diastolic (congestive) heart failure

I150.9

Heart failure unspecified

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