EBMcalc Medical Calculator

PLASMIC Score for Estimating the Likelihood of Severe ADAMTS13 Deficiency in Adults with Suspected TTP

The EBMcalc module PLASMIC Score for Estimating the Likelihood of Severe ADAMTS13 Deficiency in Adults with Suspected TTP is available in EBMcalc Complete Edition.

This calculator evaluates the following Clinical Criteria:

Platelet count <30,000/microL
One or more indicators of hemolysis:
       Reticulocyte count (percentage) >2.5%; or
       Haptoglobin undetectable; or
       Indirect bilirubin >2.0 mg/dL [>34 mcmol/L]
No active cancer in the preceding year
No history of solid organ or hematopoietic stem cell transplant
Mean corpuscular volume (MCV) <90 femtoliters
International normalized ratio (INR) <1.5
Creatinine <2.0 mg/dL [<177 mcmol/L]

References

Bendapudi PK, Hurwitz S, Fry A, et al. Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a cohort study. Lancet Haematol. 2017 Apr;4(4):e157. PubMed ID: 28259520

Legal Notices and Disclaimer

All information contained in and produced by the EBMcalc system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. EBMcalc is NOT a medical device. EBMcalc NEVER stores cookies or other persistent data in user's browsers. Click here for full notice and disclaimer.