EBMcalc Medical Calculator

Mutation and Karyotype-Enhanced International Prognostic Scoring System for Primary Myelofibrosis in adults 70 and younger (MIPSS70+ version 2.0)

The EBMcalc module Mutation and Karyotype-Enhanced International Prognostic Scoring System for Primary Myelofibrosis in adults 70 and younger (MIPSS70+ version 2.0) is available in EBMcalc Complete Edition.

This calculator evaluates the following Clinical Criteria:

Karyotype
HMR mutations
Absence of type 1/like CALR mutation
Presence of constitutional symptoms
Anemia severity
≥2% circulating blasts

References

Tefferi A, Guglielmelli P, Lasho TL, et al. MIPSS70+ Version 2.0: Mutation and Karyotype-Enhanced International Prognostic Scoring System for Primary Myelofibrosis. J Clin Oncol. 2018; 36:1769. PubMed ID: 29708808
Tefferi A, Nicolosi M, Mudireddy M, et al. Revised cytogenetic risk stratification in primary myelofibrosis: analysis based on 1002 informative patients. Leukemia. 2018; 32:1189. PubMed ID: 29472717

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