EBMcalc Medical Calculator

COVID-19 Critical Illness Predictor (Liang 5/12/2020)

Input

Age

LDH

Absolute Neutrophil Count

Absolute Lymphocyte Count

Direct Bilirubin

Comorbidities

Abnormal Chest X-ray (1.2205) Hemoptysis (1.5116) Dyspnea (0.632) Unconscious (1.5494) Presence of Cancer (1.4037)

Results

Important: Inputs must be complete to perform calculation.

Factors

Critical Illness Probability

Decimal Precision

Data action

Include literature references: Yes No

Notes

This calculator represents findings from the literature referenced below. It is important to understand that these findings may not be representative of the experience in your local healthcare system.
Comorbidities include COPD, hypertension, diabetes, coronary disease, kidney disease, cancer, cerebrovascular disease, hepatitis B and immunodeficiency.

Equations used

Factors = (Age * 0.0276) + (LDH * 0.0024) + (0.0562 * AbsoluteNeutrophilCount / AbsoluteLymphocyteCount) + (DirectBilirubin * 0.1376) + (Comorbidities * 0.4668) + CXR + Hemoptysis + Dyspnea + Unconscious + Cancer - 6.6127

CriticalIllnessProbability = 100 * e^(Factors) / (1 + e^(Factors))

References

Liang W, Liang H, Ou L, et al. Development and Validation of a Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19. JAMA Intern Med. 2020 May 12. PubMed ID: 32396163

Associated Medical Subject Headings [MeSH]

Adult, Aged, Betacoronavirus, Clinical Laboratory Techniques, Cohort Studies, Coronavirus Infections, Critical Care, Critical Illness, Female, Hospitalization, Humans, Male, Middle Aged, Pandemics, Pneumonia, Risk Assessment, Viral

Associated Logical Observation Identifiers Names and Codes [LOINC]

Parameter	LOINC's and Suggested Units
Age	21612-7 : yr 21612-7 : yr 21612-7 : years 30525-0 : Years old 30525-0 : yr 30525-0 : years
LDH	14804-9 : U/L 14805-6 : U/L 2537-9 : U/L
Absolute Neutrophil Count	751-8 : 10^3/microL 26499-4 : 10^3/microL 753-4 : 10^3/microL
Absolute Lymphocyte Count	731-0 : x10^3/microL 26474-7 : x10^3/microL 732-8 : x10^3/microL
Direct Bilirubin	1968-7 : mg/dL 14629-0 : mcmol/L

This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.

Associated HCC ICD10-CM codes

B97.29

Other coronavirus as the cause of diseases classified elsewhere

D68.69

Other Thrombophilia (COVID-19 associated hypercoagulability)

D68.8

Other Specified Coagulation Defects (COVID-19 associated coagulopathy)

J12.82

Pneumonia due to coronavirus disease

M35.81

Multisystem inflammatory syndrome.

M35.89

Other specified systemic involvement of connective tissue

U07.1

COVID-19

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